Effient® (prasugrel) can cause bleeding. If you have unexplained or excessive bleeding while on Effient, contact your doctor right away as some bleeding can be serious, and sometimes fatal. Do not take Effient if you currently have abnormal bleeding, such as stomach or intestinal bleeding, bleeding in your head, or have a history of stroke, or “mini-stroke” (also known as transient ischemic attack or TIA).
Get medical help right away if you suddenly have slurring of speech, weakness or numbness in one part of your body, blurry vision, and/or severe headache. These may be symptoms of a stroke or TIA. If you have a stroke or TIA while taking Effient, your doctor will probably stop your Effient.
Before having any surgery, you should talk to your doctor about stopping Effient. If possible, Effient should be stopped at least 1 week (7 days) before any surgery, as instructed by the doctor who prescribed Effient for you.
You may also have a higher risk of bleeding if you take Effient and you: a) are age 75 or older, b) weigh less than 132 pounds, c) are taking anticoagulants (eg, warfarin) or regular daily use of NSAIDs, d) have had recent trauma, such as an accident or surgery, e) have severe liver problems, or f) have a stomach ulcer.
Do not stop taking Effient without talking to the doctor who prescribes it for you. People who are treated with angioplasty and have a stent, and stop taking Effient too soon, have a higher risk of a blood clot in the stent, having a heart attack, or dying.
Tell your doctor about all of your medical conditions, allergies, and medicines you are taking.
Bleeding is the most common side effect of Effient.
TTP, a rare but life-threatening condition, has been reported with Effient, sometimes after a short time (less than 2 weeks). Get medical attention right away if you develop the following unexpected symptoms of TTP: fever, weakness, yellowing of the skin or eyes, or if skin becomes very pale or dotted with purple spots.
Serious allergic reactions can happen with Effient, or if you have had a serious allergic reaction to the medicines Plavix® (clopidogrel) or ticlopidine. Get medical help right away if you get any of these symptoms of a severe allergic reaction: swelling or hives of your face, lips, in or around your mouth, or throat, trouble breathing or swallowing, chest pain or pressure, dizziness or fainting.
Other side effects may occur. For more information, talk to your doctor or pharmacist.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.
For more information about Effient, please see the Full Prescribing Information, including Boxed Warning regarding bleeding risk, and Medication Guide.
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Arteries are vessels within the body that carry blood full of oxygen from the heart to different parts of your body.
A cardiologist is a doctor who specializes in treating heart disorders.
A clinical study tests the effects of medicines on study participants to determine safety and effectiveness. The study that compared Effient® (prasugrel) and Plavix® (clopidogrel bisulfate) is called TRITON-TIMI 38.
The coronary artery supplies oxygen-rich blood to your heart.
Also called acute myocardial infarction. A sudden interruption or insufficient blood supply to the heart due to a blockage in a coronary artery often characterized by severe chest pain.
Heart condition and heart disease are general terms used to describe any disorder affecting normal heart function. Acute coronary syndrome (ACS) is an example of a heart condition.
A broad term used to describe any disorder affecting normal heart function. ACS is an example of heart disease.
A procedure to open a narrowed or blocked coronary artery. Also known as angioplasty.
Platelets are blood cells that help with normal blood clotting.
A stent is a tiny, expandable tube made of metal mesh. Used to help hold an artery open, facilitating blood flow.
A procedure to open a coronary blockage that includes placement of a stent. It is a type of angioplasty.
Chest pain or discomfort that is unexpected and usually occurs while at rest.
Get tips on keeping your heart healthy.