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Effient Frequently
Asked Questions

Click one of the questions from the list below to find the answer.

How does Effient help maintain my stent?

Effient® (prasugrel) is an antiplatelet medicine. Effient taken with aspirin can help maintain your stent by keeping the platelets in your blood from sticking together and forming blood clots inside of it, and inside the arteries of your heart. Effient helps reduce the risk of a future heart-related event, such as a heart attack or blood clot in your stent, in patients who have had a heart attack or severe heart-related chest pain that was treated with angioplasty.

Because Effient reduces clotting, it can also cause bleeding. If you have unexplained or excessive bleeding while on Effient, contact your doctor right away as some bleeding can be serious, and sometimes fatal. Take your medicine for as long as your doctor prescribes.

Why do I need to take both Effient and aspirin?

Your doctor likely prescribed Effient along with aspirin. Aspirin is also an antiplatelet medicine. But it works differently than your prescription antiplatelet medicine, Effient, to help keep blood clots from forming.

Together, Effient and aspirin help reduce your risk for another serious problem with your heart or blood vessels such as heart attack, a stroke, a blood clot in your stent or death.

Because Effient reduces clotting, it can also cause bleeding. If you have unexplained or excessive bleeding while on Effient, contact your doctor right away as some bleeding can be serious, and sometimes fatal. Take your medicine for as long as your doctor prescribes.

How is Effient different from other medicines?

Each medicine plays its own unique role in your treatment, and each is important to your heart health.

Your doctor prescribed Effient because it works to help reduce the risk of blood clots forming and causing dangerous blockages inside your stent and the arteries of your heart—which is a major concern among cardiologists.

Medications for things like high blood pressure and high cholesterol do not reduce the risk of blood clots inside your stent and heart arteries. These medicines help keep your heart healthy in other ways. That's why it's very important to help protect your stent and heart arteries with Effient.

Tell your doctor about any medical conditions or allergies you may have as well as any medicines you are taking. Be sure to ask your doctor if you have questions about Effient or other medications you're taking.

What are the possible side effects of Effient?

Antiplatelet medicines like Effient reduce the ability of blood to clot, which is good when it comes to your stent and the arteries of your heart. On the other hand, because your blood doesn't clot as well, antiplatelet medicines can also increase the risk of bleeding. Bleeding is the most common side effect of Effient. Some bleeding can be life threatening and even fatal. See the Safety and Side Effects section to learn more about the safety profile of Effient.

Call your doctor right away if you have any of these signs or symptoms of bleeding:
  • Unexpected bleeding or bleeding that lasts a long time
  • Bleeding that is severe or you cannot control
  • Pink or brown urine
  • Red or black stool (looks like tar)
  • Bruises that happen without a known cause or get larger
  • Cough up blood or blood clots
  • Vomit blood or your vomit looks like “coffee grounds”

Bleeding is not the only side effect of Effient.

Thrombotic thrombocytopenic purpura (TTP), a rare but life-threatening condition, has been reported with Effient, sometimes after a short time (less than 2 weeks). Get medical attention right away if you develop the following unexpected symptoms of TTP: fever, weakness, yellowing of the skin or eyes, or if skin becomes very pale or dotted with purple spots.

Serious allergic reactions can happen with Effient, or if you have had a serious allergic reaction to the medicines Plavix® (clopidogrel) or ticlopidine. Get medical help right away if you get any of these symptoms of a severe allergic reaction: swelling or hives of your face, lips, in or around your mouth or throat, trouble breathing or swallowing, chest pain or pressure, dizziness or fainting.

Tell your doctor about any side effect that bothers you or that does not go away. These are not all the possible side effects of Effient.

If you have any problems or questions while taking Effient, talk to your doctor or pharmacist.

What can I do at home to manage possible bleeding or bruising?

Some people may bruise more easily, develop nose bleeds, or notice that cuts take longer to stop bleeding. Here are things you can try to reduce the risk of these events:
  • Try using a soft toothbrush that's a little easier on your gums
  • Consider shaving with an electric razor to reduce minor cuts
  • You may want to gently blow your nose, and/or moisturize your nostrils with a saline spray or petroleum jelly if they are unusually dry
  • Consider taking it easy around the house. You can also make some adjustments in your home to avoid bumps and bruises

Call your doctor right away if you have unexpected bleeding or bleeding that lasts a long time, or bleeding that is severe or you cannot control. Bleeding is not the only side effect of Effient.

How do I take Effient?

It is important to take Effient exactly as prescribed by your doctor. Your doctor will prescribe the right dose of Effient for you. It is also important to get your refills on time so you do not run out of medicine.
When taking Effient:
  • Take Effient one time each day
  • You can take Effient with or without food
  • Take Effient with aspirin as instructed by your doctor
  • Your doctor will decide how long you should take Effient. Do not stop taking Effient without first talking to the doctor who prescribed it for you
  • If you miss a dose, take Effient as soon as you remember. If it is almost time for your next dose, skip the missed dose. Just take the next dose at your regular time. Do not take two doses at the same time unless your doctor tells you to
  • If you take too much Effient, call your local emergency room or poison control center right away
  • Call your doctor or healthcare provider right away if you fall or injure yourself, especially if you hit your head. Your doctor or healthcare provider may need to check you

How do I store Effient?

For proper storage and handling of Effient, make sure you:
  • Keep Effient at room temperature between 59°F to 86°F (15°C to 30°C)
  • Keep Effient in the container it comes in
  • Keep the container closed tightly with the gray cylinder inside
  • Protect Effient from moisture

Keep Effient and all medicines out of the reach of children.