Indication

Effient taken with aspirin helps reduce the risk of a future heart-related event, such as a heart attack or blood clot in a stent, in patients who had an acute coronary syndrome (ACS) event that was treated with angioplasty. Effient is available in 5-mg and 10-mg tablets.

Why Effient Was Prescribed

As a new stent owner, you may ask, why do I even need to take medicine for my stent? The answer is simply this: in order to keep your heart arteries open and blood flowing, your stent must be maintained to reduce the risk of blood clots forming in your stent.

Effient® (prasugrel) maintains your stent by keeping platelets from sticking together and forming clots inside your stent and the arteries of your heart. That’s why your doctor prescribed Effient specifically for you to take once a day, every day, for as long as your doctor tells you.

Effient taken with aspirin helps reduce the risk of a future heart-related event, such as a heart attack or blood clot in a stent, in patients who had an acute coronary syndrome (ACS) event that was treated with angioplasty.

Because Effient reduces the ability of your blood to clot, it can also cause bleeding, which in some cases can be serious, and sometimes lead to death. Bleeding is not the only side effect of Effient. A generic may become available in 2017. Follow your doctor’s orders, as taking your Effient is very important to your stent and the heart arteries it supports.

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Effient works with aspirin

Your doctor likely prescribed that you take Effient along with aspirin. Aspirin is also a type of antiplatelet medicine. But it works differently than your prescription antiplatelet medicine, Effient, to help keep blood clots from forming. Together, Effient and aspirin help reduce your risk for another serious problem with your heart or blood vessels such as heart attack, a stroke, a blood clot in your stent or death.

Effient works differently than other medicines your doctor has prescribed

Each medicine your doctor prescribed plays its own unique role in your treatment and each is important to your heart health.

Medications for things like high blood pressure and high cholesterol do not reduce the risk of blood clots inside your stent and heart arteries. These medicines are important to help keep your heart healthy in other ways. Be sure to ask your doctor if you have questions about Effient or other medications you're taking.

The role high blood pressure (hypertension) medicines play in your treatment

Antihypertensives are taken to lower high blood pressure. Uncontrolled high blood pressure, often referred to as the “silent killer,” can lead to stroke, heart attack, heart failure or kidney failure. There are several classes of medications used to treat blood pressure. Some of these classes, which can be used to treat a variety of illnesses, are listed below:

Angiotensin-Converting Enzyme (ACE) Inhibitors

  • Relax and expand blood vessels, allowing blood to flow more easily
  • Allow the heart to work more easily and efficiently

Angiotensin II Receptor Blockers (ARBs)

  • Help blood vessels relax

Beta Blockers

  • Slow the heart rate
  • Improve the ability of the heart itself to relax

Calcium Channel Blockers

  • Help the heart and blood vessel muscles to relax

Diuretics

  • Help your body get rid of unneeded water and salt through your urine
  • Make it easier for your heart to pump

The role cholesterol plays in your treatment

Cholesterol-lowering medications help reduce levels of unwanted blood cholesterol.

Examples of cholesterol-lowering medications include:

Statins

  • Block the production of cholesterol
  • Help decrease blockages in the arteries

Your doctor prescribed Effient for reasons specific to you and your condition. A generic may become available in 2017. Talk to your doctor to learn more about how Effient works and why it was chosen for you.

Indication

Effient taken with aspirin helps reduce the risk of a future heart-related event, such as a heart attack or blood clot in a stent, in patients who had an acute coronary syndrome (ACS) event that was treated with angioplasty. Effient is available in 5-mg and 10-mg tablets.

Important Safety Information

What is the most important information I should know about Effient?

Effient® (prasugrel) can cause bleeding. If you have unexplained or excessive bleeding while on Effient, contact your doctor right away as some bleeding can be serious, and sometimes fatal. Do not take Effient if you currently have abnormal bleeding, such as stomach or intestinal bleeding, bleeding in your head, or have a history of stroke, or “mini-stroke” (also known as transient ischemic attack or TIA), or if you are allergic to prasugrel or any of the ingredients in Effient.

Get medical help right away if you suddenly have slurring of speech, weakness or numbness in one part of your body, blurry vision, and/or severe headache. These may be symptoms of a stroke or TIA. If you have a stroke or TIA while taking Effient, your doctor will probably stop your Effient.

Before having any surgery, you should talk to your doctor about stopping Effient. If possible, Effient should be stopped at least 1 week (7 days) before any surgery, as instructed by the doctor who prescribed Effient for you.

You may also have a higher risk of bleeding if you take Effient and you: a) are age 75 or older, b) weigh less than 132 pounds, c) are taking anticoagulants (eg, warfarin) or regular daily use of NSAIDs, d) have had recent trauma, such as an accident or surgery, e) have severe liver problems, f) have moderate to severe kidney problems, or g) have a stomach ulcer.

Call your doctor right away if you have any of these signs or symptoms of bleeding: unexpected bleeding or bleeding that lasts a long time, bleeding that is severe or you cannot control, pink or brown urine, red or black stool, bruises that happen without a known cause or get larger, cough up blood or blood clots or vomit blood or your vomit looks like coffee grounds.

Do not stop taking Effient without talking to the doctor who prescribes it for you. People who are treated with angioplasty and have a stent, and stop taking Effient too soon, have a higher risk of a blood clot in the stent, having a heart attack, or dying.

What should I tell my doctor before taking Effient?

Tell your doctor about all of your medical conditions, allergies, and medicines you are taking.

What are the possible side effects of Effient?

Bleeding is the most common side effect of Effient.

TTP, a rare but life-threatening condition, has been reported with Effient, sometimes after a short time (less than 2 weeks). Get medical attention right away if you develop the following unexpected symptoms of TTP: fever, weakness, yellowing of the skin or eyes, or if skin becomes very pale or dotted with purple spots.

Serious allergic reactions can happen with Effient, or if you have had a serious allergic reaction to the medicines Plavix® (clopidogrel) or ticlopidine. Get medical help right away if you get any of these symptoms of a severe allergic reaction: swelling or hives of your face, lips, in or around your mouth, or throat, trouble breathing or swallowing, chest pain or pressure, dizziness or fainting.

Other side effects may occur.

Effient is available by prescription only. For more information, talk to your healthcare provider or pharmacist.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

For more information about Effient, please see the Full Prescribing Information, including Boxed Warning regarding bleeding risk, and Medication Guide.

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Important Safety Information

What is the most important information I should know about Effient?

Effient® (prasugrel) can cause bleeding. If you have unexplained or excessive bleeding while on Effient, contact your doctor right away as some bleeding can be serious, and sometimes fatal. Do not take Effient if you currently have abnormal bleeding, such as stomach or intestinal bleeding, bleeding in your head, or have a history of stroke, or “mini-stroke” (also known as transient ischemic attack or TIA), or if you are allergic to prasugrel or any of the ingredients in Effient.

Get medical help right away if you suddenly have slurring of speech, weakness or numbness in one part of your body, blurry vision, and/or severe headache. These may be symptoms of a stroke or TIA. If you have a stroke or TIA while taking Effient, your doctor will probably stop your Effient.

Before having any surgery, you should talk to your doctor about stopping Effient. If possible, Effient should be stopped at least 1 week (7 days) before any surgery, as instructed by the doctor who prescribed Effient for you.

You may also have a higher risk of bleeding if you take Effient and you: a) are age 75 or older, b) weigh less than 132 pounds, c) are taking anticoagulants (eg, warfarin) or regular daily use of NSAIDs, d) have had recent trauma, such as an accident or surgery, e) have severe liver problems, f) have moderate to severe kidney problems, or g) have a stomach ulcer.

Call your doctor right away if you have any of these signs or symptoms of bleeding: unexpected bleeding or bleeding that lasts a long time, bleeding that is severe or you cannot control, pink or brown urine, red or black stool, bruises that happen without a known cause or get larger, cough up blood or blood clots or vomit blood or your vomit looks like coffee grounds.

Do not stop taking Effient without talking to the doctor who prescribes it for you. People who are treated with angioplasty and have a stent, and stop taking Effient too soon, have a higher risk of a blood clot in the stent, having a heart attack, or dying.

What should I tell my doctor before taking Effient?

Tell your doctor about all of your medical conditions, allergies, and medicines you are taking.

What are the possible side effects of Effient?

Bleeding is the most common side effect of Effient.

TTP, a rare but life-threatening condition, has been reported with Effient, sometimes after a short time (less than 2 weeks). Get medical attention right away if you develop the following unexpected symptoms of TTP: fever, weakness, yellowing of the skin or eyes, or if skin becomes very pale or dotted with purple spots.

Serious allergic reactions can happen with Effient, or if you have had a serious allergic reaction to the medicines Plavix® (clopidogrel) or ticlopidine. Get medical help right away if you get any of these symptoms of a severe allergic reaction: swelling or hives of your face, lips, in or around your mouth, or throat, trouble breathing or swallowing, chest pain or pressure, dizziness or fainting.

Other side effects may occur.

Effient is available by prescription only. For more information, talk to your healthcare provider or pharmacist.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

For more information about Effient, please see the Full Prescribing Information, including Boxed Warning regarding bleeding risk, and Medication Guide.