Indication

Effient taken with aspirin helps reduce the risk of a future heart-related event, such as a heart attack or blood clot in a stent, in patients who had an acute coronary syndrome (ACS) event that was treated with angioplasty. Effient is available in 5-mg and 10-mg tablets.

Heart-Healthy Living

Eating well and exercising regularly are key to managing several risk factors for heart disease. To get free heart-healthy recipes and tips on how to maintain a healthy lifestyle, sign up for Esstential Habits®.

Take your medicines as prescribed

It is important to take all of your medicines, including Effient® (prasugrel), exactly as prescribed by your doctor. Each medicine in your regimen is there for a reason. It is also important to get your refills on time so you do not run out of medicine.

If you smoke, quit

If you smoke a pack of cigarettes a day, your risk of having a heart attack is more than twice that of a person who has never smoked. Smoking also increases the risk for sudden cardiac death in people with coronary heart disease. Your doctor can recommend the best method for you to stop smoking.

Manage your calories

If your doctor recommends that you lose weight, first learn how many calories you should consume to maintain your desired weight. Then adjust your diet and increase your level of activity. Your doctor can help determine the right plan for you. Learn more about typical calorie consumption from the American Heart Association site.

Watch your cholesterol levels

Desired cholesterol levels vary by the individual. Work with your doctor to find the right cholesterol level for you.

Eat a balanced diet

To achieve a balanced, heart-healthy diet, try nutrient-rich foods like vegetables, fruits, whole-grain foods, low-fat or fat-free dairy products, fish, lean meats or poultry.

Don't worry. Eating healthier doesn't have to be complicated or expensive. The food you prepare at home can be fun, relaxing, economical, and most important, healthier than restaurant meals. When you cook in your own kitchen, you have greater control over how the food is prepared, as well as over the fat content, total calories and nutrition level.

Here are some examples of ways to eat healthy:

  • Gather recipes and cookbooks that focus on keeping your heart in good health
  • Choose “choice” or “select” cuts of beef and remove excess fat
  • Choose leaner, light meat like chicken breasts; avoid dark meat such as legs and thighs, which have more fat; and always remove the skin before cooking
  • For egg dishes, substitute two egg whites for each egg yolk
  • Choose low-fat or fat-free milk, yogurt and cheese
  • Choose reduced-fat, low-fat, light or no-fat salad dressings
  • Reduce your salt intake

Read food labels

By reading food labels carefully, you can avoid foods with “empty” calories, which are foods high in calories but relatively low in essential nutrients. When examining labels, be aware of foods that contain undesirable ingredients such as sodium, saturated fats, added sugars and trans fats. Learn more about how to read food labels from the U.S. Food and Drug Administration site.

Ease into exercise

Exercise is a proven way to modify your risk factors for heart disease and help maintain overall mental and physical health. By making exercise a regular part of your daily routine, you may enjoy any or all of these benefits:

  • Strengthened heart and lungs
  • Improved circulation
  • Increased endurance
  • Lowered blood pressure

Tips for a successful exercise program

As you begin exercising, consider these tips to help make your recovery as successful as possible.

Take it slow

It's great to be enthusiastic about exercise, just don't get carried away too soon. Work with your doctor to determine what level of exercise is right for you.

Keep it fun and comfortable

Why not get your exercise doing something you like? It could be working out at the gym, walking, dancing, biking or even working in the yard or garden. To make exercise even more enjoyable, try wearing loose, comfortable clothes and supportive footwear, and try listening to your favorite music while you exercise.

Get some support

Finding an exercise “buddy” is a great way to keep motivated. Even when no workout partner is available, you can still look to friends and family for support and encouragement. All you have to do is ask.

Mix it up

Identify a variety of activities you enjoy and switch between them on a regular basis. That way you'll avoid the risk of exercise seeming boring or stale.

You can also get your exercise while doing household chores like vacuuming, dusting and mowing the lawn.

Create a schedule

Even the best fitness program is worthless if you can never seem to fit it into your day. Find the best location and most convenient time to plan your workout. Then make it a priority by writing it into your daily schedule. Of course, there will be times when you can't keep your exercise “appointment.” When that happens, just get back on track the next day.

Note your success

Note your exercise activity so you can track your progress and success. When you achieve a milestone, do something to reward yourself. You should enjoy the good job you're doing.

Go by the numbers

It's a lot easier to exercise properly and measure your progress when you know two important numbers: your BMI and your target heart rate. BMI is a measure of your weight scaled according to your height. Learn more about BMI from the American Heart Association site. Check with your doctor to determine your target heart rate, and you can then monitor your pulse while exercising.

Indication

Effient taken with aspirin helps reduce the risk of a future heart-related event, such as a heart attack or blood clot in a stent, in patients who had an acute coronary syndrome (ACS) event that was treated with angioplasty. Effient is available in 5-mg and 10-mg tablets.

Important Safety Information

What is the most important information I should know about Effient?

Effient® (prasugrel) can cause bleeding. If you have unexplained or excessive bleeding while on Effient, contact your doctor right away as some bleeding can be serious, and sometimes fatal. Do not take Effient if you currently have abnormal bleeding, such as stomach or intestinal bleeding, bleeding in your head, or have a history of stroke, or “mini-stroke” (also known as transient ischemic attack or TIA), or if you are allergic to prasugrel or any of the ingredients in Effient.

Get medical help right away if you suddenly have slurring of speech, weakness or numbness in one part of your body, blurry vision, and/or severe headache. These may be symptoms of a stroke or TIA. If you have a stroke or TIA while taking Effient, your doctor will probably stop your Effient.

Before having any surgery, you should talk to your doctor about stopping Effient. If possible, Effient should be stopped at least 1 week (7 days) before any surgery, as instructed by the doctor who prescribed Effient for you.

You may also have a higher risk of bleeding if you take Effient and you: a) are age 75 or older, b) weigh less than 132 pounds, c) are taking anticoagulants (eg, warfarin) or regular daily use of NSAIDs, d) have had recent trauma, such as an accident or surgery, e) have severe liver problems, f) have moderate to severe kidney problems, or g) have a stomach ulcer.

Call your doctor right away if you have any of these signs or symptoms of bleeding: unexpected bleeding or bleeding that lasts a long time, bleeding that is severe or you cannot control, pink or brown urine, red or black stool, bruises that happen without a known cause or get larger, cough up blood or blood clots or vomit blood or your vomit looks like coffee grounds.

Do not stop taking Effient without talking to the doctor who prescribes it for you. People who are treated with angioplasty and have a stent, and stop taking Effient too soon, have a higher risk of a blood clot in the stent, having a heart attack, or dying.

What should I tell my doctor before taking Effient?

Tell your doctor about all of your medical conditions, allergies, and medicines you are taking.

What are the possible side effects of Effient?

Bleeding is the most common side effect of Effient.

TTP, a rare but life-threatening condition, has been reported with Effient, sometimes after a short time (less than 2 weeks). Get medical attention right away if you develop the following unexpected symptoms of TTP: fever, weakness, yellowing of the skin or eyes, or if skin becomes very pale or dotted with purple spots.

Serious allergic reactions can happen with Effient, or if you have had a serious allergic reaction to the medicines Plavix® (clopidogrel) or ticlopidine. Get medical help right away if you get any of these symptoms of a severe allergic reaction: swelling or hives of your face, lips, in or around your mouth, or throat, trouble breathing or swallowing, chest pain or pressure, dizziness or fainting.

Other side effects may occur.

Effient is available by prescription only. For more information, talk to your healthcare provider or pharmacist.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

For more information about Effient, please see the Full Prescribing Information, including Boxed Warning regarding bleeding risk, and Medication Guide.

Top

Important Safety Information

What is the most important information I should know about Effient?

Effient® (prasugrel) can cause bleeding. If you have unexplained or excessive bleeding while on Effient, contact your doctor right away as some bleeding can be serious, and sometimes fatal. Do not take Effient if you currently have abnormal bleeding, such as stomach or intestinal bleeding, bleeding in your head, or have a history of stroke, or “mini-stroke” (also known as transient ischemic attack or TIA), or if you are allergic to prasugrel or any of the ingredients in Effient.

Get medical help right away if you suddenly have slurring of speech, weakness or numbness in one part of your body, blurry vision, and/or severe headache. These may be symptoms of a stroke or TIA. If you have a stroke or TIA while taking Effient, your doctor will probably stop your Effient.

Before having any surgery, you should talk to your doctor about stopping Effient. If possible, Effient should be stopped at least 1 week (7 days) before any surgery, as instructed by the doctor who prescribed Effient for you.

You may also have a higher risk of bleeding if you take Effient and you: a) are age 75 or older, b) weigh less than 132 pounds, c) are taking anticoagulants (eg, warfarin) or regular daily use of NSAIDs, d) have had recent trauma, such as an accident or surgery, e) have severe liver problems, f) have moderate to severe kidney problems, or g) have a stomach ulcer.

Call your doctor right away if you have any of these signs or symptoms of bleeding: unexpected bleeding or bleeding that lasts a long time, bleeding that is severe or you cannot control, pink or brown urine, red or black stool, bruises that happen without a known cause or get larger, cough up blood or blood clots or vomit blood or your vomit looks like coffee grounds.

Do not stop taking Effient without talking to the doctor who prescribes it for you. People who are treated with angioplasty and have a stent, and stop taking Effient too soon, have a higher risk of a blood clot in the stent, having a heart attack, or dying.

What should I tell my doctor before taking Effient?

Tell your doctor about all of your medical conditions, allergies, and medicines you are taking.

What are the possible side effects of Effient?

Bleeding is the most common side effect of Effient.

TTP, a rare but life-threatening condition, has been reported with Effient, sometimes after a short time (less than 2 weeks). Get medical attention right away if you develop the following unexpected symptoms of TTP: fever, weakness, yellowing of the skin or eyes, or if skin becomes very pale or dotted with purple spots.

Serious allergic reactions can happen with Effient, or if you have had a serious allergic reaction to the medicines Plavix® (clopidogrel) or ticlopidine. Get medical help right away if you get any of these symptoms of a severe allergic reaction: swelling or hives of your face, lips, in or around your mouth, or throat, trouble breathing or swallowing, chest pain or pressure, dizziness or fainting.

Other side effects may occur.

Effient is available by prescription only. For more information, talk to your healthcare provider or pharmacist.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

For more information about Effient, please see the Full Prescribing Information, including Boxed Warning regarding bleeding risk, and Medication Guide.